NYU Data Catalog

NYU Dataset

Authors: Yvonne Vallès

Claire K. Inman

Brandilyn A. Peters

Raghib Ali

24 more author(s)...
Description: This dataset includes 330 Emirati adults participating in the UAE Healthy Future Study-Pilot (UAEHFS-pilot) who provided mouthwash samples. There were 225 non-smokers and 105 smokers who used cigarettes, dokha, shisha, or a combination of tobacco products. 101 of the 105 smokers were male. Tobacco use and frequency were assessed with a structured questionnaire and urine cotinine lab results. Gene...
Subject: Health Status

Risk Factors
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NYU Dataset

Authors: Daniel Ardeljan

Xuya Wang

Mehrnoosh Oghbaie

Martin S. Taylor

15 more author(s)...
Description: This study showed that long interspersed element-1 (LINE-1) ORF2p expression is almost undetectable in human cancers. LINE-1 is the major driver of mobile DNA activity in humans. When expressed, LINE-1 loci produce bicistronic transcripts encoding two proteins essential for retrotransposition, ORF1p and ORF2p. ORF2p expression is not well characterized in human tissues and cell lines. For the study,...
Subject: Genomics

Proteomics
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NYU Dataset

Authors: Wilson McKerrow

Zuojian Tang

Jared P. Steranka

Lindsay M. Payer

5 more author(s)...
Description: This dataset was compiled to determine a genome-wide long interspersed element-1 (LINE-1) insertion site mapping method for bulk DNA. This study has shown that transposon insertion profiling by sequencing (TIPseq) is a method that can be used for LINE-1 mapping in single cells. For the study, live GM12878 lymphoblastoid cells were obtained from Coriell Institute for Medical Research. The dataset contains...
Subject: Genomics
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NYU Dataset

Authors: Andrew T. Timberlake

Casey Griffin

Carrie L. Heike

Anne V. Hing

25 more author(s)...
Description: This dataset was collected to study the genetic cause of craniofacial microsomia (CFM), which is the second most common congenital facial anomaly. In this study, they performed whole exome or genome sequencing of 146 kindreds with sporadic or familial CFM. Blood or saliva samples were collected from the proband and DNA was extracted from blood and saliva using standard procedures. This resulted in...
Subject: Genomics
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NYU Dataset

Authors: Eileen M. Boyle

Shayu Deshpande

Ruslana Tytarenko

Cody Ashby

19 more author(s)...
Description: Smoldering multiple myeloma (SMM) is an asymptomatic plasma cell disorder. It is associated with a high-risk of progression to multiple myeloma (MM). For this study, they performed targeted sequencing on 82 patients. The results showed fewer NRAS and FAM46C mutations with SMM, which is consistent with their role as drivers of the transition to MM. They also analyzed the change in clonal structure over...
Subject: Cancer

Genomics
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Authors: Vincent W. V. Jaddoe

Generation R Study Group
Description: Generation R is an ongoing prospective cohort study of child development from the prenatal period through young adulthood in a multi-ethnic population recruited from the Rotterdam, Netherlands metropolitan area. The study enrolled 9,778 mothers with a delivery date between April 2002 and January 2006; they had 9,749 live births. The primary objective of the study is to identify early environmental...
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Local Expert: Akhgar Ghassabian

NYU Dataset

Authors: Zhi Fang

Xiaoran Sun

Xiang Wang

Ji Ma

6 more author(s)...
Description: Cerebral cavernous malformation (CCM) lesions are caused by loss of function of CCM genes. Previous study showed that NOGOB receptor (NGBR) knockout in endothelial cells (ECs) results in cerebrovascular lesions in the mouse embryo. However, the molecular mechanism by which NGBR regulates CCM1/2 expression has not been explained. This study revealed that genetic depletion of NGBR in ECs results in CCM1/2...
Subject: Genomics
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